nannamom Admin
Number of posts : 2210 Age : 66 Humor : Once you choose hope, anything’s possible. -Christopher Reeve Registration date : 2008-11-09
| Subject: Now this is interesting Wed 10 Feb 2010, 9:29 pm | |
| While searching the Internet tonight for an article having to do with constipation and some remedies to help with constipation I came across an article that talks about Naloxone when combined with Prolonged release Oxycodone can actually counteract opioid induced constipation. This is something that I had never heard of and of course I wanted to share it with all of you. Read below. As always comments are welcome. Another new medication for severe pain (long-term pain that can be experienced as a result of conditions such as back pain, arthritis and osteoarthritis), are tablets combining prolonged release oxycodone, an opioid which treats pain, and prolonged release naloxone, a compound which counteracts the potential negative effects of the opioid on the GI function (available as TarginactTM). This novel combination has been proven to provide equivalent pain relief to oxycodone alone, whilst significantly improving bowel function. Naloxone is an opioid receptor antagonist that, when taken orally, has negligible systemic bioavailability8 providing a full inhibitory effect on local opioid receptors in the gut - counteracting opioid-induced constipation - without impacting on the centrally acting analgesic efficacy of oxycodone.References: Medical News TodayImage borrowed from the Wyeth Library from the Medical news today website. posted by Dee | |
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